Research Focuses:
Our lab applies a multidisciplinary approach to 1)Elucidate the mechanisms and functions of epigenetic modifications including methylation and acetylation; 2) Rational design and synthesize selective and potent inhibitors for methyltransferases and acetyltransferases; 3) Develop novel therapeutic agents for cancer and other diseases through targeting epigenetic pathways.
Project 1: Targeting Methyltransferases to discover new drugs
Project 2: Targeting Protein α-N-terminal Acetylation
Project 2: Targeting Protein α-N-terminal Acetylation